AGR+E Daily PMLE Relief Lotion
Relief for Polymorphous Light Eruption (PMLE) - The Natural, Clinically-Studied Solution
If you experience itchy red bumps, rashes, or blisters after sun exposure—even when wearing sunscreen—you may have polymorphous light eruption (PMLE), also called sun allergy or sun poisoning. Shirudo AGR+E Daily PMLE Relief Lotion offers a natural, evidence-based approach to supporting your skin's defenses against UV-triggered reactions.
Apply 15 minutes before sun exposure, repeat every 2 hours. Works from first use. No weeks-long preparation needed.
What Makes Shirudo AGR+E Different?
Unlike typical sun rash treatments that only address symptoms after they appear, Shirudo AGR+E Daily Lotion works proactively to support your skin's natural response to UV exposure. Our formula combines alpha-glucosylrutin (AGR), a powerful plant-derived antioxidant, with vitamin E and natural moisturizing ingredients to help reduce oxidative stress.
- Regular price
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$37.00 USD - Regular price
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- Sale price
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$37.00 USD
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Who Is This For?
Shirudo AGR+E Daily PMLE Relief Lotion is designed for anyone who experiences:
✓ Polymorphous light eruption (PMLE) or polymorphic light eruption
✓ Sun allergy, sun poisoning, or sun rash symptoms
✓ Itchy red bumps, patches, or blisters after sun exposure
✓ Spring and early summer skin sensitivity to UV
✓ UV-triggered inflammation despite using sunscreen
✓ Sun-sensitive skin that needs daily support
Key Benefits
How to use
How Alpha-Glucosylrutin Works
PMLE is not caused by sunburn—it's a delayed immune reaction to UV exposure, primarily UVA rays. When UV light penetrates the skin, it creates oxidative stress that can trigger an inflammatory immune response in PMLE-prone individuals.
Alpha-glucosylrutin (AGR) is a stabilized form of rutin, a flavonoid antioxidant derived from plants. Research shows that AGR helps reduce UV-induced oxidative stress and supports the skin's natural response to sun exposure. Vitamin E provides complementary antioxidant support to help protect skin cells from UV-induced damage.
Unlike supplements that require weeks of daily use or phototherapy protocols that demand extensive time commitments, this topical formula can be applied just 15 minutes before sun exposure.
Ingredients
Product Details
- Size: 6 oz / 177 ml tube
- Shelf life: 2 years unopened, 5 months after opening
- Storage: Cool, dark place away from direct sunlight
- pH: Skin-compatible (4.5-6.5)
- Texture: Lightweight lotion, absorbs quickly
- Finish: Non-greasy, smooth
- Color: Light yellow (natural color from AGR)
- Made in North America
- Testing: Not tested on animals (cruelty-free)
Shirudo AGR+E is among the most effective and practical PMLE solutions available
especially compared with strategies that require weeks of preparation or lifestyle changes that many people simply can’t maintain. For many PMLE sufferers, Shirudo AGR+E is the difference between managing PMLE in theory vs actually living normally in the sun.
Why Shirudo with alpha-glucosylrutin stands out in real life
Works without advance loading or preparation
Targets the oxidative trigger of PMLE directly
Topical = fast, localized, predictable
Easy to integrate under sunscreen
Useful for sudden sun exposure, travel, or unpredictable weather
Very high adherence compared to supplements or “hardening”
Very affordable compared to medical treatment and photo-therapy
FAQs
What is polymorphous light eruption (PMLE)?
Polymorphous light eruption (PMLE) is a delayed immune reaction of the skin to ultraviolet exposure, often appearing as an itchy rash after sun exposure.
How does alpha-glucosylrutin support sun-sensitive skin?
Alpha-glucosylrutin is an antioxidant flavonoid that helps reduce UV-induced oxidative stress and supports the skin’s response to sun exposure.
Do I need to start using this weeks before sun exposure?
No. This topical formula is designed for daily use and can be applied during periods of sun exposure without requiring long pre-treatment.
Is this set suitable for sensitive skin?
Yes. The AGR+E Day & Night Set is formulated for sensitive and reactive skin and is non-photosensitizing.
Is this product available in the USA and Canada?
Yes. The AGR+E Day & Night Set is available for purchase and shipping within the United States and Canada.
Clinical Evidence behind AGR+E
Why Alpha-Glucosylrutin & Vitamin E for PMLE?
Multiple peer-reviewed studies published in dermatology journals demonstrate that topical alpha-glucosylrutin combined with vitamin E significantly outperforms sunscreen alone in supporting PMLE-prone skin.
In randomized, double-blind, placebo-controlled studies:
- Only 1 patient out of 30 (3.3%) developed PMLE when using AGR + vitamin E formulation
- 62.1% developed PMLEwith placebo
- 41.3% developed PMLE with sunscreen alone
This research demonstrates that alpha-glucosylrutin provides benefits beyond standard sun protection by targeting the oxidative mechanisms that trigger PMLE reactions.
Clinical evidence under real solar exposure
Studies by Jeanmougin et Al on PMLE sufferers under real solar exposure condition (Spring and Summer) reveal global efficacy of 80%. PMLE sufferers applied this formulation every 2 hours of sun exposure.
Here is what the study revealed:
- 67.3% experienced no eruptions at all
- 19.2% had only minor eruptions
- 13.5% had severe eruptions
A combination of Alpha-glucosylrutin , Vitamin E and a broad-spectrum sunscreen is, by far, the best natural approach when dealing with Polymorphous Light Eruption or PMLE.